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Feline Lower Urinary Tract Disease

More Than Half of Cats With Urinary Trouble Had It Again — and the Cause Was Not Always the Same

In 101 cats followed for a median of just over three years, 58% had a recurrence, and 14 cats turned out to have a different underlying cause at a later episode.

Feline Lower Urinary Tract DiseaseLow evidence
Source
Journal of Feline Medicine and Surgery, 2019
Study type
Retrospective owner-interview follow-up study
PAWai use
EducationalObservation Support
Last reviewed
September 2, 2026
Next scheduled review
September 2, 2027
Version
Topic v1.0 · Knowledge v1.0
⚠ Not for decision-making — for education and visit preparation only

Plain-English summary

Urinary trouble in cats has an unusual property: the signs look much the same regardless of what is causing them. Straining, going often, blood in the urine, urinating outside the tray, crying in the tray — these appear whether the underlying problem is inflammation, a stone, or an infection.

This 2019 study followed 101 cats after they were first seen for such signs. More than half of those with a firm diagnosis had at least one recurrence, some of them repeatedly.

And in fourteen cats, a later episode had a different cause from the earlier one. That is the finding worth carrying away, because it undercuts a very natural assumption — that if your cat has had this before, you already know what it is.

What the study found

Data were collected from cats presented with lower urinary tract signs between 2010 and 2013, with follow-up by telephone interview with owners using a structured questionnaire. The observation period ran from first presentation to the interview or the cat's death.

The study included 101 cats. Fifty-two were diagnosed with feline idiopathic cystitis, 21 with urolithiasis and 13 with a bacterial urinary tract infection; 15 had no definitive diagnosis.

Among the 86 cats with a known diagnosis, the recurrence rate was 58.1%, with no significant difference between the diagnosis groups. Twenty-one cats had one relapse, twelve had two, ten had three, and seven had between four and eight, over a median observation period of 38 months (range 0.5–138 months).

Fourteen cats suffered from different causes of lower urinary tract disease at different episodes.

Mortality attributed to the disease across all 101 cats was 5.0% — which the authors note is lower than previously reported.

In cats with urolithiasis, those receiving at least two prophylactic measures had a significantly lower recurrence rate than those receiving none (P = 0.029).

The authors' conclusion is directed at practice: cats should be thoroughly investigated at each presentation, since it cannot be presumed that the cause is the same at different episodes.

What this study cannot tell you

One hundred and one cats is a small sample, and the subgroups are smaller still — thirteen cats with bacterial infection, twenty-one with stones. The prophylactic-measures finding rests on part of that 21-cat group, so its precision is limited even though the p-value is significant.

Follow-up came from owner telephone interviews, some of them years after the events. Owners recalling whether and when a cat had a urinary episode is a softer measure than clinical records, and recurrences that were mild or never presented to a vet may be missed or misremembered.

The observation period ranged enormously, from 0.5 to 138 months. A cat followed for six months and one followed for eleven years contribute very differently to a recurrence rate, and a single overall percentage flattens that.

The study describes cats that were referred and diagnosed. It does not tell you the recurrence risk for a cat whose episode resolved without a firm diagnosis, and 15 of its own cats fell into that category and were excluded from the recurrence figure.

Finally, it reports what happened, not why. It identifies no cause of recurrence and tests no treatment beyond the observational prophylaxis comparison.

What pet owners should track

Because episodes look alike but may not be alike, a dated record of each one is genuinely useful to a veterinarian:

  • The date each episode started and how long the signs lasted
  • What exactly you observed — straining, frequent small volumes, blood, urinating outside the tray, crying or vocalising in the tray, excessive licking
  • What was diagnosed that time, and what was prescribed
  • Whether the signs resolved fully or only partly
  • Any prophylactic measures in place — diet, water intake, litter tray changes, environmental adjustments — and when each was started
  • For multi-cat homes, note that you may not be able to attribute what you find in a shared tray to one cat, and say so rather than assuming

A cat straining to urinate and producing little or nothing may be blocked. That is an emergency — contact a veterinarian immediately. It is most common in male cats and can become life-threatening within hours.

What PAWai can help organize

An episode history is exactly what this study says clinicians need at each presentation, and exactly what is hardest to reconstruct in a consulting room eighteen months later. PAWai holds each episode with its date, your description, the diagnosis given and what was tried. PAWai does not diagnose urinary disease, cannot tell you which cause you are looking at, and does not advise on diet or prophylaxis. As this study shows, the causes are clinically indistinguishable from the signs alone — that is precisely why each episode needs investigating rather than assuming. What PAWai contributes is that the previous episodes arrive intact.

Disclaimer

PAWai organizes information and educates pet owners. PAWai does not diagnose conditions or recommend treatment. Always consult a licensed veterinarian for medical decisions about your pet.

Citation

Kaul, E., Hartmann, K., Reese, S., & Dorsch, R. (2019). Recurrence rate and long-term course of cats with feline lower urinary tract disease. Journal of Feline Medicine and Surgery, 22(6), 544–556. https://doi.org/10.1177/1098612X19862887

Frequently asked questions

My cat had this once and recovered. Is it likely to come back?

In this study it often did. Among the 86 cats with a known diagnosis, 58.1% had at least one recurrence during a median follow-up of 38 months. Twenty-one had one relapse, twelve had two, ten had three, and seven had between four and eight.

If it comes back, is it the same problem as before?

Not necessarily, and this is the study's most practical finding. Fourteen of the cats had different causes of their urinary signs at different episodes. The authors conclude that cats should be thoroughly investigated at each presentation rather than assuming the previous diagnosis still applies.

Which cause was most common?

Of the 101 cats, 52 were diagnosed with feline idiopathic cystitis, 21 with urolithiasis and 13 with a bacterial urinary tract infection. Fifteen had no definitive diagnosis. Recurrence rates did not differ significantly between the diagnosis groups.

Do preventive measures help?

In one subgroup, yes. Cats with urolithiasis that received at least two prophylactic measures had a significantly lower recurrence rate than those receiving none (P = 0.029). That is a single subgroup finding in a small study, and which measures to use is a decision for your veterinarian.

When is this an emergency?

A cat straining in the litter tray and producing little or no urine may have a blocked urethra. This is most common in male cats and is life-threatening within hours. Contact a veterinarian immediately — do not wait, and do not observe overnight. This warning is standing veterinary safety guidance, not a finding of this particular study.

Sources

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